Message #1990

[Boreas]

     
Early Eurasians in northwest Siberia revealed by mitochondrial DNA analysis.

Olga A Derbeneva , Elena B Starikovskaya , Douglas C Wallace , Rem I Sukernik

The mtDNA of 98 Mansi were analyzed. The Mansi-people is an ancient group formerly known as "Voguls". They are Uralic-speaking fishers and hunters on the eastern slope of the northern Ural Mountains were analyzed.

63.3% of the mtDNA detected in the Mansi falls into western Eurasian lineages (e.g., haplogroups UK, TJ, and HV). The remaining 36.7% encompass a subset of eastern Eurasian lineages (e.g., haplogroups A, C, D, F, G, and M).

Among the western Eurasian lineages, subhaplogroup U4 was found at a remarkable frequency of 16.3%, along with lineages U5, U7, and J2. This suggests that the aboriginal populations residing immediately to the east of the Ural Mountains may encompass remnants of the early Upper Paleolithic expansion from the Middle East/southeastern Europe. The added presence of eastern Eurasian mtDNA lineages in the Mansi introduces the possibilities that proto-Eurasians encompassed a range of macrohaplogroup M and N lineages that subsequently became geographically distributed. The Paleolithic expansion may have reached this part of Siberia from the west, - before it split into western and eastern human groups.

Mesh-terms: Asia, ethnology; DNA, Mitochondrial, genetics; Ethnic Groups, genetics; Europe, ethnology; Gene Frequency; Haplotypes, genetics; Human; Phylogeny; Polymorphism, Restriction Fragment Length; Siberia, ethnology; Support, Non-U.S. Gov't; Support, U.S. Gov't, P.H.S.;

Mitochondrial DNA variation in Kets and Nganasans and the early peoples of Northern Eurasia

O A Derbeneva , E B Starikovskaia , N V Volod'ko , D C Wallace , R I Sukernik

Mitochondrial DNA variation was studied in 38 Kets and 24 Nganasans, the indigenous inhabitants of the north of the Yenisey River Basin and the Taimyr Peninsula. The results were compared with the analogous data obtained for 59 Kondinski and 39 Sos'vinski Mansi. As a whole, mitochondrial gene pool of Mansi, Nganasans, and Kets was characterized by unique combination of European-specific (H, H2, H3, H8, U2, U4, U5, U7, J2, and W) and Asian-specific (A, C, D, and Z) mtDNA haplogroups. Specific features of the haplogroup geographical distribution along with the results of phylogenetic reconstruction favor the hypothesis of the genetic trace left in Eastern Cis-Urals and the adjacent Siberian territories by early migrations from the western Eurasia.

http://lib.bioinfo.pl/meid:146407